HISTOLOGICAL ANALYSIS OF THE EFFECT OF BURITI OIL ON EXPERIMENTAL ENVENOMATION BY Bothrops moojeni SNAKE VENOMTITLE

Authors

DOI:

https://doi.org/10.20873/pibic_2024_21132

Abstract

Brazil has the highest incidence of snakebite accidents in South America, with Tocantins being the state with the highest number of reported cases in the northern region of the country. Accidents caused by the Bothrops genus account for approximately 90% of the cases, and the most affected individuals are young male workers in rural areas, with significant socioeconomic consequences. Bothrops venom has proteolytic, necrotic and hemorrhagic effects, and the recommended treatment is serum therapy. However, logistical problems and the distance from health centers make immediate treatment difficult, worsening the damage caused by the venom. Research has demonstrated the potential of buriti oil (Mauritia flexuosa) as a natural and complementary alternative for the treatment of snakebite accidents. An experimental study with mice demonstrated the reparative potential of the oil in changes induced by the venom of the Bothrops moojeni snake. The research continued with the aim of evaluating the protective effect of buriti oil at the histological level, on skeletal and cardiac muscle tissue, using a protocol that combines the ingestion and local application of the oil in poisoned animals. The results indicated that treatment with buriti oil protected the muscle fibers, reducing the damage caused by the poison.

Author Biographies

Larissa Calazans Pereira, Universidade Federal do Tocantins

Graduanda do curso de Ciências Biológicas, Campus de Porto Nacional

Hemilly Cirqueira Martins, Universidade Federal do Tocantins

Doutoranda do curso de Pós-Graduação em Ciências do Ambiente, Universidade Federal do Tocantins (UFT)

Patrícia Siqueira de Melo Rodrigues, Universidade Federal do Tocantins

Doutora em Ciências do Ambiente, Universidade Federal do Tocantins (UFT)

Kellen Lagares Ferreira Silva, Universidade Federal do Tocantins

Doutora em Botânica, Professora do Curso de Ciências Biológicas e do Programa de Pós-Graduação em Ciências do Ambiente, Universidade Federal do Tocantins (UFT)

Carla Simone Seibert, UFT

Curso de Ciências Biológicas, Campus de Porto Nacional - UFT

Published

2025-04-30

How to Cite

Pereira, L. C., Martins, H. C., Rodrigues, P. S. de M., Silva, K. L. F., & Seibert, C. S. (2025). HISTOLOGICAL ANALYSIS OF THE EFFECT OF BURITI OIL ON EXPERIMENTAL ENVENOMATION BY Bothrops moojeni SNAKE VENOMTITLE. DESAFIOS - Revista Interdisciplinar Da Universidade Federal Do Tocantins, 12(1), 1–15. https://doi.org/10.20873/pibic_2024_21132

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