Lethality in Culex quinquefasciatus of secondary compounds of species from the Cerrado region of Tocantins Copaifera reticulata, Pterodon emarginatu
DOI:
https://doi.org/10.20873/jbb.uft.cemaf.v10n2.santosKeywords:
Culex, extract, secondary metabolic, lethalityAbstract
Forest resources are of great importance in the search for products with an environmental bias in the path of sustainable development with the extraction of native resources available mainly in the cerrado Tocantinense, and they also have secondary metabolic with promising photochemical against disease-transmitting mosquitoes. The objectives of this work were to analyze the lethal concentrations LC50 and LC90 in third-stage larvae of Culex quinquefasciatus insects, with the inoculation of crude extract oil from Copaifera reticulata, Pterodon emarginatus. The extraction of crude oil from Copaifera reticulata was by core drilling, and from Pterodon emarginatus by fried pressing. The bioassay of lethal concentrations was diluted in DMSO (dimethyl sufoxide), inoculated into larvae at different concentrations, and analyzed for lethality after 24 hours. The results for LC50 Copaifera reticulata were 190.79 ppm and 392.84 ppm. Pterodon emarginatus presented LC50 and LC90 values of 84.80 ppm and 198.09 ppm. The LC50 and LC90 ecotoxicity demonstrated larvicidal potential against Culex quinquefasciatus larvae, with Pterodon emarginatus oil having the lowest lethal concentration.
References
Abed RA, Cavasin GM, Silva HHG, Geris R, Silva IG. Alte-rações morfohistológicas em larvas de Aedes aegypti (Lin-naeus, 1762) (Diptera, Culicidae) causadas pela atividade larvicida do óleo-resina da planta medicinal Copaifera reti-culata Ducke (Leguminosae). Revista de Patologia Tropi-cal/Journal of Tropical Pathology, v.36, n.1, p.75-85, 2007. https://doi.org/10.5216/rpt.v36i1.1819
Alves KF, Caetano FH, Garcia IJP, Santos HL, Silva DB, Siqueira JM, Tanaka AS, Alves SN. Baccharis dracunculi-folia (Asteraceae) essential oil toxicity to Culex quinquefas-ciatus (Culicidae). Environmental Science and Pollution Re-search, v.25, n.31, p.31718-31726, 2018. https://doi.org/10.1007/s11356-018-3149-x
Al-Mekhlafi FA. Larvicidal, ovicidal activities and histopatho-logical alterations induced by Carum copticum (Apiaceae) extract against Culex pipiens (Diptera: Culicidae). Saudi journal of biological sciences, v.25, n.1, p.52-56, 2018. https://doi.org/10.1016/j.sjbs.2017.02.010
Amarante CBD, Müller AH, Póvoa MM, Dolabela MF. Estu-do fitoquímico biomonitorado pelos ensaios de toxicidade frente à Artemia salina e de atividade antiplasmódica do cau-le de aninga (Montrichardia linifera). Acta Amazonica, v.41, n.3, p.431-434, 2011. https://doi.org/10.1590/S0044-59672011000300015
Souza LB, Barros JR. Agronegócio e ambiente no Cerrado tocantinense: um panorama dos municípios com base em indicadores. Ateliê Geográfico, v.13, n.1, p.124–149, 2019. https://doi.org/10.5216/ag.v13i1.51961
Cabral SS. Atividade larvicida do extrato bruto de Swinglea glutinosa evidenciada pelas alterações morfohistológicas em larvas de Aedes aegypti (Diptera, Culicidae). 2015. 42 p. Dissertação (Mestrado em Biologia da Relação Parasito-Hospedeiro) - Universidade Federal de Goiás, Goiânia.
Cansian RL, Staudt A, Bernardi JL, Puton BMS, Oliveira D, Oliveira JV, Gomes ACC, Andrade BCOP, Leal ICR, Si-mas NK, Zeni J, Jungues A, Dallago RM, Backes GT, Pa-roul N. Toxicity and larvicidal activity on Aedes aegypti of citronella essential oil submitted to enzymatic esterification. Brazilian Journal of Biology, v.83, p.1-5, 2021. https://doi.org/10.1590/1519-6984.244647
Menezes AAT, Beltrão TS, Silva LS, Silva HHG, Silva IG, Paula JR, Romano CA, Guissoni ACP. Chemical composi-tion, larvicidal activity and residual effect of Pterodon polygalaeflorus (Benth.) Benth. (Fabaceae) fruit oil extracts against Aedes aegypti (Diptera: Culicidae). Revista de Pato-logia Tropical/Journal of Tropical Pathology, v.48, n.4, p.225-232, 2019. https://doi.org/10.5216/rpt.v48i4.62119
Dias CN, Moraes DFC. Essential oils and their compounds as Aedes aegypti L. (Diptera: Culicidae) larvicides. Parasito-logy research, v.113, n.2, p.565-592, 2014. https://doi.org/10.1007/s00436-013-3687-6
Faria AM, Santos AS, Ferreira LL, Bastos TSA, Louly CCB, Matos MPC, Conceição EC, Moura VMBD. Acaricidal ac-tivity of ethanolic extracts of Stryphnodendron adstringens and Lafoensia pacari and oil resins from Copaifera sp. and Pterodon emarginatus against Sarcoptes scabiei var. suis. Pesquisa Veterinária Brasileira, v.37, n.12, p.1411-1415, 2017. https://doi.org/10.1590/S0100-736X2017001200009
Fernandes DA. Estudo fitoquímico de Helicteres velutina K. Schum (Sterculiaceae) e avaliação do seu potencial larvicida contra Aedes aegypti L. (Diptera: Culicidae). 2017.136 f. Dissertação (Mestrado em Produtos Naturais e Sintéticos Bioativos) - Universidade Federal da Paraíba, João Pessoa.
Geris R, Silva IGD, Silva HHGD, Barison A, Rodrigues-Filho E, Ferreira AG. Diterpenos de Copaifera reticulata Ducke com atividade larvicida contra Aedes aegypti (L.) (Diptera, Culicidae). Revista do Instituto de Medicina Tropi-cal de São Paulo, v.50, n.1, p.26-28, 2008. https://doi.org/10.1590/S0036-46652008000100006
Guedes DRD, Paiva MHS, Donato MMA, Barbosa PP, Krokovsky L, Rocha SWS, Saraiva KLA, Crespo MM, Re-zende TMT, Wallau GL, Barbosa RMR, Oliveira CMF, Melo-Santos MAV, Pena L, Cordeiro, MT, Franca RFO, Oliveira ALS, Peixoto CA, Leal WS, Ayres CFJ. Zika virus replication in the mosquito Culex quinquefasciatus in Brazil. Emerging microbes & infections, v.6, n.1, p.1-11, 2017. https://doi.org/10.1038/emi.2017.59
Holder P, Browne G, Bullians M. The mosquitoes of New Zealand and their animal disease significance. Surveillance, v.26, n.4, p.12-15, 1999.
Izumi E, Ueda-Nakamura T, Veiga-Júnior VF, Nakamura CV. Toxicity of oleoresins from the genus Copaifera in Trypano-soma cruzi: a comparative study. Planta medica, v.79, n.11, p.952-958, 2013. https://doi: 10.1055/s-0032-1328712
Kanis LA, Prophiro JS, Silva Vieira E, Nascimento MP, Zepon KM, Kulkamp-Guerreiro IC, Silva OS. Larvicidal activity of Copaifera sp. (Leguminosae) oleoresin microcap-sules against Aedes aegypti (Diptera: Culicidae) larvae. Pa-rasitology research, v.110, n.3, p.1173-1178, 2012. https://doi.org/10.1007/s00436-011-2610-2
Lai CH, Tung KC, Ooi HK, Wang JS. Competence of Aedes albopictus and Culex quinquefasciatus as vector of Dirofi-laria immitis after blood meal with different microfilarial density. Veterinary Parasitology, v.90, n.3, p.231-237, 2000. https://doi.org/10.1016/S0304-4017(00)00242-9
Leandro LM, Sousa Vargas F, Barbosa PCS, Neves JKO, Silva JA, Veiga-Junior FV. Chemistry and biological activi-ties of terpenoids from copaiba (Copaifera spp.) oleoresins. Molecules, v.17, n.4, p.3866-3889, 2012. https://doi.org/10.3390/molecules17043866
Mandal S. Effect of Azadirachta indica A. Juss (Meliaceae) seed oil and extract against Culex quinquefasciatus Say (Diptera: Culicidae) larval susceptibility of Indian subconti-nent. Macedonian Journal of Medical Sciences, v.4, n.1, p.5-11, 2011. https://doi:10.3889/MJMS.1857-5773.2011.0127
Martins WS, Muraishi CT. Aspectos biométricos, grau de umidade em sementes de sucupira e determinação do efeito fungitóxico do seu óleo essencial. Revista Integralização Universitária, n.20, p.17-24, 2019. https://doi.org/10.31501/1982-9280.2019V13N20p.17-24
Morais SAD, Marrelli MT, Natal D. Aspectos da distribuição de Culex (Culex) quinquefasciatus Say (Diptera, Culicidae) na região do rio Pinheiros, na cidade de São Paulo, estado de São Paulo, Brasil. Revista Brasileira de Entomologia, v.50, p.413-418, 2006. https://doi.org/10.1590/S0085-56262006000300012
Silva WJ, Dória GAA, Maia RT, Nunes RS, Carvalho GA, Blank AF, Alves PB, Marçal RM, Cavalcanti SCH. Effects of essential oils on Aedes aegypti larvae: alternatives to envi-ronmentally safe insecticides. Bioresource technology, v.99, n.8, p.3251-3255, 2008. https://doi.org/10.1016/j.biortech.2007.05.064
Noleto PF, Noleto PC, Sousa KF, Guimarães APM. Influên-cia das queimadas para a qualidade orgânica de duas áreas do cerrado tocantinense. Natural Resources, v.10, n.1, p.1-9, 2020. https://doi.org/10.6008/CBPC2237-9290.2020.001.0001
Oliveira JA, Garcia L, Silva HHG, Silva IG. Toxicity of hex-anic and methanolic fractions from Copaifera reticulata ducke (Leguminosae–Caesalpinoidea) against Aedes aegypti Linnaeus (Diptera–Culicidae), in field assays. Revista de Patologia Tropical/Journal of Tropical Pathology, v.45, n.2, p.203-211, 2016.
Oliveira AE, Duarte JL, Amado JR, Cruz RA, Rocha CF, Souto RN, Carvalho JC. Development of a larvicidal nanoemulsion with Pterodon emarginatus Vogel oil. PLoS One, v.11, n.1, p.1-16, 2016. https://doi.org/10.1371/journal.pone.0145835
Oliveira AEMFM, Duarte JL, Cruz RAS, Souto RNP, Ferrei-ra RMA, Peniche T, Conceição EC, Oliveira LAR, Faustino SMM, Florentino AC, Carvalho JCT, Fernandes CP. Pter-odon emarginatus oleoresin-based nanoemulsion as a prom-ising tool for Culex quinquefasciatus (Diptera: Culicidae) control. Journal of Nanobiotechnology, v.15, n.1, p.1-11, 2017. https://doi.org/10.1186/s12951-016-0234-5
Pimenta ATA, Santiago GMP, Arriaga AMC, Menezes GHA, Bezerra SB. Estudo fitoquímico e avaliação da atividade lar-vicida de Pterodon polygalaeflorus Benth (Leguminosae) sobre Aedes aegypti. Revista Brasileira de Farmacognosia, v.16, n.4, p.501-505, 2006. https://doi.org/10.1590/S0102-695X2006000400011
Pizarro APB, Oliveira Filho AM, Parente JP, Melo MTV, Santos CE, Lima PR. O aproveitamento do resíduo da in-dústria do sisal no controle de larvas de mosquitos. Revista da Sociedade Brasileira de Medicina Tropical, v.32, n.1, p.23-29, 1999. https://doi.org/10.1590/S0037-86821999000100005
Rodrigues ECR, Ferreira AM, Vilhena JCE, Almeida FB, Cruz RAS, Florentino AC, Souto RNP, Carvalho JCT, Fer-nandes CP. Development of a larvicidal nanoemulsion with Copaiba (Copaifera duckei) oleoresin. Revista Brasileira de Farmacognosia, v.24, p.699-705, 2014. https://doi.org/10.1016/j.bjp.2014.10.013
Rodrigues FA, Pimenta VSC, Braga KMS, Araújo EG. Ob-tenção de extratos de plantas do cerrado. Enciclopédia Bios-fera, v.13, n.23, p.1-18, 2016. https://doi:10.18677/Enciclopedia_Biosfera_2016_075
Santos DB. Atividade larvicida da Copaifera langsdorffii (Leguminosae), evidenciada pelas alterações morfohistológi-cas em Aedes aegypti (Diptera, Culicidae). 2015. 71 p. Dis-sertação (mestrado em Biologia das Interações Parasito-Hospedeiro) - Universidade Federal de Goiás, Goiânia.
Santos ELVS. Atividade larvicida da nanoemulsão do óleo essencial de Ocimum basilicum Linn (Lamiales: Lamiacea) em Aedes aegypti Linnaeus e Culex quinquefasciatus Say (Diptera: Culicidae). 2018. 63 p. Dissertação (Mestrado Programa de Pós-Graduação em Ciências da Saúde) – Uni-versidade Federal do Amapá, Amapá.
Silva JG, Guimarães VP, Lima CG, Silva HHG, Elias CN, Mady CM, Silva VVM, Nery AP, Rocha KR, Rocha C, Isac E. Efeito larvicida e toxicológico do extrato bruto etanó-lico da casca do caule de Magonia pubescens sobre Aedes aegypti (Diptera, Culicidae), em criadouros artificiais. Revis-ta de Patologia Tropical/Journal of Tropical Pathology, v.32, n.1, p.73-86, 2003. https://doi.org/10.5216/rpt.v32i1.4353
Silva IG, Zanon VOM, Silva HHG. Larvicidal Activity of Copaifera reticulata Ducke Oil-Resin against Culex quin-quefasciatus Say (Diptera: Culicidae). Neotropical Entomo-logy, v.32, n.4, p.729-732, 2003. https://doi.org/10.1590/S1519-566X2003000400029
Silva HHG, Geris R, Rodrigues Filho E, Rocha, C, Silva IG. Larvicidal activity of oil-resin fractions from the Brazilian medicinal plant Copaifera reticulata Ducke (Leguminosae-Caesalpinoideae) against Aedes aegypti (Diptera, Culicidae). Revista da Sociedade Brasileira de Medicina Tropical, v.40, n.3, p.264-267, 2007.
Silva ES. Análise dos aspectos socioeconômicos, fito-demográficos, genéticos e físico-químicos da extração do óleo-resina de Copaifera reticulata em duas comunidades da Flona do Tapajós, Pará. 2011. 98p. Tese (Doutorado em Bi-otecnologia) - Universidade Federal do Amazonas, Manaus.
Silva TPD. Obtenção e avaliação da atividade larvicida da nanoemulsão do óleo essencial de Hyptis suaveolens (L.) Poit. Sobre Aedes aegypti e Culex quinquefasciatus (Dipte-ra: Culicidae). 2017. 83 p. Dissertação (Mestrado em Biodi-versidade Tropical) – Departamento de Pós-Graduação, Universidade Federal do Amapá, Macapá.
Silveira JC, Busato NV, Costa AOS, Junior Costa EF. Levan-tamento e análise de métodos de extração de óleos essenci-ais. Enciclopédia Biosfera, v.8, n.15, p.2038-2049, 2012.
Teixeira FB, Brito SR, Lameira OA, Webber LP, D’Almeida CRS, Martins MD, Lima RR. Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats’ tongues. BMC complementary and alternative medicine, v.17, n.1, p.1-8, 2017. https://doi.org/10.1186/s12906-017-1820-2
Trindade FTT, Stabeli RG, Pereira AA, Facundo VA, Silva AA. Copaifera multijuga ethanolic extracts, oilresin, and its derivatives display larvicidal activity against Anopheles dar-lingi and Aedes aegypti (Diptera: Culicidae). Revista Brasi-leira de farmacognosia, v.23, n.3, p.464-470, 2013. https://doi.org/10.1590/S0102-695X2013005000038
Valotto CFB, Silva HHG, Cavasin G, Geris R, Rodrigues Filho E, Silva IG. Alterações ultraestruturais em larvas de Aedes aegypti submetidas ao diterpeno labdano, isolado de Copaifera reticulata (Leguminosae), e à uma fração rica em taninos de Magonia pubescens (Sapindaceae). Revista da Sociedade Brasileira de Medicina Tropical, v.44, n.2, p.194-200, 2011. https://doi.org/10.1590/S0037-86822011005000010
Valotto CFB, Cavasin G, Silva HHG, Geris R, Silva IG. Atividade larvicida do ácido 3-β-acetoxylabdan-8 (17)-13-dien-15-óico isolado da planta medicinal Copaifera reticula-ta (leguminosae) sobre Aedes aegypti (diptera, culicidae) evidenciada pelas alterações morfohistológicas. Revista de Patologia Tropical, Goiânia, GO, vol.43, n.3, p.375-384, 2014. https://doi:10.5216/rpt.v43i3.32214
Vidal PO, Peruzin MC, Suesdek L. Wing diagnostic charac-ters for Culex quinquefasciatus and Culex nigripalpus (Dip-tera, Culicidae). Revista Brasileira de Entomologia, v.55, n.1, p.134-137, 2011. https://doi.org/10.1590/S0085-56262011000100022
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Thiago César Santos, Damiana Beatriz Silva, Ana Cristina de Menezes, Dalmarcia de Souza Carlos Mourão, Augustus Caeser Franke Portella, Marcos Giongo
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2024 - Journal of Biotechnology and Biodiversity
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY 4.0 at http://creativecommons.org/licenses/by/4.0/) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (Available at The Effect of Open Access, at http://opcit.eprints.org/oacitation-biblio.html).