Cochlospermum regium: conservation and chemical and biological activity
DOI:
https://doi.org/10.20873/jbb.uft.cemaf.v8n3.menezesKeywords:
Cochlospermaceae, savanna Cerrado domain, endangered flora, plant endemismAbstract
Cochlospermum regium is an important plant species for both floristic and herbal medicine. The species has seed development and protocols for breaking dormancy and high germination rates are necessary, since it is a plant explored daily in the field, where the population and root gatherers seek the terrestrial organ (rhizome or xylopodium) for the preparation of bottles and powder for consumption, used to relieve and treat numerous infectious forms. Thus, the work aimed to raise bibliographic data from studies among them, articles, books, master's dissertations on the conservation of the species observing data on the dormancy break and germination, and on the chemical and biological activities exerted by the numerous ways in which the species. Plant organs of C. regium are used. Through the reviews it was possible to verify numerous germination protocols and several works that aimed to identify the classes of compounds and their biological activities. In this review it is possible to observe that C. regium is extensively studied allowing new drugs and food preservation through antioxidant and microbial actions to enable the use of this plant species. In addition, the protocols presented in this study have high germination rates and may help future reforestation projects and inclusion of C. regium in other environments or even in other biomes perpetuating the species.
References
Abedi M, Bartelheimer M, Poschlod P. Effects os substrate type, moisture and its interations on soil seed survival of three Rumex species. Plant and Soil, v.374, n.1-2, p.485-495, 2014. https://doi.org/10.1007/s11104-013-1903-x
Albuquerque MCF, Coelho MFB, Albrecth JMF. Germinação de sementes de espécies medicinais do Cerrado. In: I Semi-nário Matogrossense de etnobiologia e etnoecologia e II Seminário Centro-Oeste de plantas medicinais. 2002.
Almeida SCX, Lemos TLG, Silveira ER, Pessoa ODL. 2005. Volatile and non-volatile chemical constituents of Cochlo-spermum vitifolium (Willdenow) Ssprengel. Química Nova, v.28, p.57-60, 2005. http://dx.doi.org/10.1590/S0100-40422005000100012
Andrade LS, Santos DB, Castro DB, Guillo LA, Chen-Chen L. Absence of antimutagenicity of Cochlospermum regium (Mart. and Schr.) Pilger 1924 by micronucleus test in mice. Brazilian Journal of Biology, v.68, n.1, p.155-159, 2008. http://dx.doi.or/10.1590/S1519-69842008000100022
Apezzato-da-Glória B, Carmello-Guerreiro SM. Plant Anato-my. 2ª Ed., UFV: Viçosa, p.438, 2006.
Arunachalam K, Damazo AS, Pavan E, Oliveira DM, Figuei-redo FF, Machado MT, Blogun SO, Soares IM, Barbosa RS, Alvim TC, Ascêncio SD, Martins DTO. Cochlosper-mum regium (Mart. ex Schrank) Pilg.: Evaluation of chemi-cal profile, gastroprotective activity mechanism of action of hidroethanolic extract of its Xylopodium in acute and chron-ic experimental models. Journal Ethnopharmacology, v.233, p.101-114, 2019. https://doi.or/10.1016/j.jep.2019.01.002
Bambi P, Rezende RS, Cruz TMS, Batista JEA, Miranda FGG, Dos Santos LV, Júnior JFG. Diversidade da flora fanerogâmica de três matas de galeria no bioma Cerrado. Heringeriana, v.10, n.2, p.147-167, 2016.
Batista PF, Costa AC, Megguer CA, Lima JS, Sales JF. Over-coming dormancy and characterization of germination in Cerrado ‘algodãozinho’ seeds treated with dimethyl sulph-oxide. South African Journal of Botany, v.92, p.89-93, 2014. https://doi.org/10.1016/j.sajb.2014.02.004
Bueno ML, Oliveira-Filho AT, Pontara V, Pott V, Pott A, Damasceno-Júnior GA. Flora arbórea do Cerrado de Mato Grosso do Sul. Iheringia, v.73 (supl.), p.53-64, 2018. https://doi.org/10.21826/2446-8231201873s53
Bueso E, Munoz-Bertomeu J, Campos F, Brunaud V, Mar-tinez L, Sayas E, Ballester P, Yenush L, Serrano R. Ara-bidopsis thaliana HOMEOBOX25 uncovers a role for gib-berellins in seed longevity. Plant Physiology, v.164, n.2, p.999-1010, 2014. https://doi.org/10.1104/pp.113.232223
Brasil. Presidência da República, Casa Civil, Subchefia para Assunto Jurídicos, Lei nº. 12.651, de 25 de maio de 2012. Brasília, 25 de maio de 2012; 191º da Independência e 124º da República. http://www.planalto.gov.br/ccivil_03/_ato2011-2014/2012/lei/l12651.htm. Acesso em 22 de julho de 2020.
Camillo J, Scherwinski-Pereira JE, Vieira RF, Peixoto JR. Conservação in vitro de Cochlospermum regium (Schrank) Pilg.-Cochlospermaceae sob regime de crescimento mínimo. Revista Brasileira de Plantas Medicinais, v.11, n.2, p.184-189, 2009. https://doi.org/10.1590/S1516-05722009000200012
Carvalho RS, Carollo CA, Magalhães JC, Palumbo JMC, Boaretto AG, Nunes e Sá IC, Ferraz AC, Lima WG, De Si-queira JM, Ferreira JMS. Antibacterial and antifungal activi-ties of phenolic compound-enriched ethyl acetate fraction from Cochlospermum regium (Mart. et Schr.) Pilger roots: Mechanisms of action and synergism with tannin and gallic acid. South African Journal of Botany, v.114, p.181-187, 2018. https://doi.org/10.1016/j.sajb.2017.11.010
Castro MAS, Siqueira JM, Krieger-Amorin LW, Souza KCB. Efeito analgésico e antiedematogênico do Cochlospermum regium (Mart.) Pilger (‘algodãozinho’). In: Medicinal Plants Symposium of Brazil, v.13, Universidade Federal do Ceará, Fortaleza, Ceará, 1994.
Ceschini L, Campos ÉG. Cytotoxic effects of Cochlospermum regium (Mart e Schrank) Pilger aqueous root extrct on mammalian cells. Journal of Ethnopharmacology, v.103, p.302-305, 2006. https://doi.org/10,1016/j.jep.2005.07.026
Coelho MdeFB, Sales DM, Albuquerque MCF. Germinação e emergência de Cochlospermum regium (Schrank) Pilg. em diferentes substratos. Revista Brasileira de Plantas Medici-nais, v.10, n.4, p.90-96, 2008.
Coelho MdeFB, Sales DM, Dombroski JLD, De Azevedo RAB, Albuquerque MCdeFe. Condições de luz e tempera-tura na germinação de sementes de algodão do campo [Cochlospermum regium (Schrank) Pilger – Bixaceae]. Re-vista de Biologia Neotropical, v.5, n.2, p.23-31, 2008. https://doi.org/10.5216/rbn.v5i2.9814
Cunha-Laura AL, Oliveira RJ, De Barros ALC, De Siqueira JM, Vieira MdoC, Auharek SA. Maternal exposure to Cochlospermum regium: a toxicological evaluation. Revista Brasileira de Farmacognosia, v.23, n.2, p.374-378, 2013. https://doi.org/10.1590/S0102-695X2013005000005
Cushine TP, Lamb AJ. Antimicrobial activity of flavonoids. International Journal of Antimicrobial Agents, v.26, n.5, p.343-356, 2005. https://doi.org/10.1016/j.ijantimicag.2005.09.002
De Oliveira VB, Mezzomo TR, De Moraes EF. Conhecimento e uso de plantas medicinais por usuários de unidade básicas de saúde na região de Colombo, PR. Revista Brasileira de Ciências da Saúde, v.22, n.1, p.57-64, 2018. https://doi.org/10.22478/ufpb.2317-6032.2018v22n1.30038
Duarte MR, Oliveira RB, Dranka ERK, Yano M. Anatomia foliar de algodãozinho-do-cerrado: Cochlospermum regium (Schrank) Pilg., Bixaceae. Visão Acadêmica, v.15, n.2, p.5-16, 2014. http://dx.doi.org/10.5380/acd.v15i2.38312
Dzoyem JP, Hamamoto H, Ngameni B, Ngadjui BT, Sekimizu K. Antimicrobial action mechanism of flavonoids from Dor-stenia species. Drug Discoveries e Therapeutics, v.7, n.2, p.66-72, 2013. https://doi.org/10.5582/ddt.2013.v7.2.66
Edenharder R, Rauscher R, Platt KL. The inhibition by flavo-noids of 2-amino-3-methylimidazo [4,5-f] quinoline meta-bolic activation to a mutagen: a structure-activity relationship study. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, v.379, n.1, p.21-32, 1997. https://doi.org/10.1016/S0027-5107(97)00085-7
E Silva JLSC, Bicudo BP, Rodrigues AB, Mendonça MMM, Borges, RR, De Almeida AA, De Oliveira KMP. Evaluation of antibacterial and antifungal activity of ethanolic extract of Cochlospermum regium (Cochlospermaceae) leaf, a medici-nal plant from the Cerrado of Brazil. In: 5th Congress of the Brazilian Biotechnology Society, BioMed Central, BMC Proceedings, v.8, (Suppl 4), p.72, 2014.
Firmo WCA, Miranda MV, Coutinho GSL, Silveira LMS, Olea RSG. Estudo fitoquímico e avaliação da atividade anti-bacteriana de Lafoensia pacari (Lythraceae). Publicatio UEPG, Ciências Biológicas e da Saúde, v.20, n.1, p.7-12, 2014. https://doi.org/10.5212/publicatio%20uepg.v20i1.6541
Gobbo-Neto L, Lopes NP. Plantas medicinais: fatores de influência no conteúdo de metabólitos secundários. Química Nova, v.30, n.2, p.374-381, 2007. http://dx.doi.org/10.1590/S0100-40422007000200026
Goulas V, Exarchou V, Kanetis L, Gerothanassis IP. Evalua-tion of the phytochemical content, antioxidant activity and antimicrobial properties of mountain tea (Sideritis syryaca) decotion. Journal of Functional Foods, v.6, n.1, p.248-258, 2014. https://10.1016/j.jff.2013.10.014
Hartmann HT, Kester DE, Davies Jr FT, Geneve RL. Plant propagation: principles and pratices. 6th Ed., Prentice Hall, New Jersey, 770 p., 1997.
Honda NK, Brum RL, Hess SC, Cru AB, Moretto E. Antibac-terial activity of Cochlospermum regium essential oil. Fitot-erapia, v.68, n.1, p.79-80, 1997.
Ho KY, Tsai CC, Huang JS, Chen CP, Lin TC, Lin CC. An-timicrobial activity of tannin components of Vaccinium vitis-idaea L. Journal of Pharmacy and Pharmacology, v.53, n.2, p.187-191, 2001. https://doi.org/10.1211/0022357011775389
Imanishi H, Sasaki YF, Ohta T, Watanabe M, Kate T, Shirasu Y. Tea tannin components modify the induction of sister-chromatid exchanges and chromosome aberrations in muta-gen-treated cultured mammalian cells and mice. Mutation Research/Genetic Toxicology, v.259, n.1, p.79-87, 1991. https://doi.org/10.1016/-165-1218(91)90111-x
Inácio MC, Bertoni BW, Franca SC, Pereira MAS. In vitro seeds germination and ex vitro plants development of al-godãozinho-do-campo. Ciência Rural, v.40, n.11, p.2294-2300, 2010.
Inácio MC, Paz TA, Bertoni BW, Pereira AMS. Germination of Cochlospermum regium seeds: influence os seed size, vials, vial sealing in vitro, and substrate in vivo. European Journal of Medicinal Plants, v.6, n.1, p.26-33, 2015. https://doi.org/10.9734/EJMP/2015/15077
Inácio MC, Paz TA, Bertoni BW, Vieira MAR, Marques MOM, Pereira MAS. Histochemical investigation of Cohlo-spermum regium (Schrank) Pilg. leaves and chemical com-position of its essential oil. Natural Product Research, v.28, n.10, p.727-731, 2014. http://dx.doi.or/10.1080/14786419.2013.879133
Inácio MC, Bertoni BW, França SC, Pereira MAS. In vitro conservation and low cost micropropagation of Cochlo-spermum regium (Mart. ex. Scharank). Journal of Medicinal Plants Research, v.5, n.20, p.4999-5007, 2011.
Inácio MC. Agronomic, chemical and biological study Cochlospermum regium (Mart. ex Scharank): A medicinal plant of the cerrado. Dissertação de mestrado. Universidade Estadual Paulista, p.118, 2010.
Inácio MC, Paz TA, Bertoni BW, Pereira MAS. Effect of environmental and phenological factors on the antimicrobial activity of Cochlospermum regium (Schrank) Pilg. roots. Acta Scientiarum, v.38, n.4, p.467-473, 2016. http://dx.doi.org/10.4025/actasciagron.v38i4.30567
Joly AB. Botânica: introdução à taxonomia vegetal. 13ª Ed., São Paulo: Ed. Nacional, 2002.
Kaeser MJ, Kiskman LK. Seed longevity of 12 native herba-ceous species in a fire-maintained pine savanna after 8 years of burial. Forest Ecology and Management, v.281, n.1, p.68-74, 2012. https://doi.org/10.1016/j.foreco.2012.06.019
Kirizawa M. Contribuição ao conhecimento morfo-ecológico e do desenvolvimento anatômico dos órgãos vegetativos e de reprodução de Cochlospermum regium (Mart. e Sch.) Pilger – Cochlospermaceae. Tese doutorado. Universidade de São Paulo, 436 p., 1981.
Leonardi M, Giovanelli S, Cioni PL, Flamini G, Pistelli L. Evaluation of volatile constituents of Cochlospermum ango-lense. Natural Product Communictions, v.7, p.629-632, 2012. https://doi.org/10.1177/1934578X1200700522
Leme DEM, Rodrigues AB, Almeida-Apolonio AA, Dantas FGS, Negri MFN, Svidzinski TIE, Mota JS, Cardoso CAL, De Oliveira KMP. In vitro control of uropathogenic micro-organisms with the rthanolic extract from the leaves of Cochlospermum regium (Schrank) Pilger. Evidence-Based Complementary and Alternative Medicine, p.1-8, 2017. https://doi.org/10.1155/2017/4687154
Lewis AC, Hanson PJ. 4 Anti-ulcer drugs of plant origin. Progress in Medicinal Chemistry, v.28, p.201-231, 1991. https://doi.org/10.1016/S0079-6468(08)70365-5
Lima DP, Castro MAS, Mello JCP, Siqueira JM, Kassab NM. A flavanone glycoside from Cochlospermum regium. Fitot-erapia, v.66, p.545-546, 1995.
Menezes Filho ACP, Castro CFS. Avaliação dos extratos vegetais de Cochlospermum regium em um Cerrado ralo. Global Science and Technology, v.13, n.01, p.01-17, 2019.
Menezes Filho, ACP, Santos MC, Castro CFS. Estudo fitoquímico, bioativo, fotoprotetor e físico-químico do extra-to floral do extrato floral de algodãozinho do Cerrado [Cochlospermum regium Schrank. (Pilg.)] – Bixaceae. Re-vista Arquivos Científicos, v.3, n.4, 2020.
Myers N, Mittermeier RA, Mittermeier CG, Fonseca GAB, Kent J. Biodiversity hotspots for conservations priorities. Nature, v.403, n.6772, p.853-858, 2000. https://doi.org/10.1038/35002501
Neto GG. Cochlospermaceae regium (Mart. e Schrank) Pilger – Bixaceae. FLOVET – Boletim do Grupo de Pesquisa da Flora, Vegetação e Etnobotânica, v.1, n.8, p.27-34, 2016.
Noronha MRP, Gottsberger GA. A polinização de Aspilia floribunda (Asteraceae) e Cochlospermum regium (Cochlo-spermaceae) e a relação das abelhas visitantes com outras plantas do cerrado de Botucatu, Estado de São Paulo. Re-vista Brasileira de Botânica, v.3, n.1/2, p.67-77, 1980.
Noleto PF, Noleto PC, de Sousa KF, Guimarães APM. In-fluência das queimadas para a qualidade orgânica de duas áreas do Cerrado tocantinense. Natural Resources, v.10, n.1, p.1-9, 2020. http://doi.org/10.6008/CBPC2237-9290.2020.001.0001
Nunes WB, Carvalho S. Evaluation of the mutagenic potential of Cochlospermum regium in Drosophila melanogaster male germ cells. Genetics and Molecular Biology, v.26, n.4, p.545-549, 2003. http://dx.doi.org/10.1590/S1415-47572003000400020
Nunes GP, Silva MF, Resende UM, Siqueira JM. Plantas medicinais comercializadas por raizeiros no centro de Cam-po Grande, Mato Grosso do Sul. Revista Brasileira de Far-macognosia, v.13, n.2, p.83-92, 2003. https://doi.org/10.1590/S0102-695X2003000200004
Pedroso TFM, Bonamigo TR, Da Silva J, Vasconcelos P, Félix JM, Cardoso CAL, Souza RIC, Dos Santos AC, Vo-lobuff CRF, Formagio ASN, Trichez VDK. Chemical con-stituents of Cochlospermum regium (Schrank) Pilg. root and its antioxidant, antidiabetic, antiglycation, and anticholines-terase effects in Wistar rats. Biomedicine e Pharmacothera-py, v.111, p.1383-1392, 2019. https://doi.org/10.1016/j.biopha.2019.01.005
Pessoa C, Costa-Lotufo LV, Leyva A, De Moraes MEA, De Moraes MO. Anticancer potential of northeast brazilian plants. Advances in Phytomedicine, v.2, p.197-211, 2006. https://doi.org/10.1016/S1572-557X(05)02012-X
Pereira C, Barros L, Alves MJ, Pereira L, Santos-Buelga C, Ferreira ICFR. Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum an-golensis Welw. Industrial Crops and Products, v.74, p.412-416, 2015. https://doi.org/10.1016/j.indcrop.2015.05.056
Poppendieck H-H. Cochlospermaceae. New York Botanical Gardens, Bronx NY, 1981.
Portis IG, Figueiredo FRG, Pena RV, Hanusch AL, De Sousa LP, Machado RC, De Silva CC, Da Cruz AD. Bioensaio citogenético para a caracterização da mutagenicidade e ci-totoxicidade da espécie Cochlospermum regium. Revista Eletrônica da Faculdade de Ceres, v.5, n.1, 2016. https://doi.org/10.36607/refacer.v5i1.3357
Ribeiro JF, Walter BMT. As principais fitofisionomias do Bioma Cerrado. In Cerrado: ecologia e flora (Sano SM, Al-meida SP, Ribeiro JF, eds.). Embrapa Cerrados, Planaltina, 151-212 p. 2008.
Ritto JLA, Oliveira FD, Carvalho JED, Dias PC. Avaliação farmacológica do extrato fluido de Cochlospermum regium (Mart. et Schr.) Pilger. Lecta-USF, v.14, n.2, p.27-36, 1996.
Ritto JLA. Caracterização farmacológica da droga e do extrato fluído de algodãozinho-do-campo-Cochlospermum regium (Marte t Schr) Pilger. Dissertação de mestrado, universidade de São Paulo, 1996.
Ritto JLA, Kato ETM. Estudo morfo-histológico de raízes de algodãozinho-do-campo Cochlospermum regium (Mart. et. Schr.) Pilger. Lecta, v.16, p.97-109, 1998.
Sales DM, Coelho MFB, Albuquerque MCF, Ferronato A. Superação da dormência por ácido sulfúrico em sementes de algodão do campo Cochlospermum regium (Mart. e Schr.) Pilg. – Cochlospermaceae. Revista Brasileira de Plantas Medicinais, v.4, p.65-71, 2002.
Sales DM. Germinação de sementes de [Cochlospermum regium (Mart. ex Schr.) Pilg.] Cochlospermaceae. Dis-sertação de mestrado. Universidade Federal do Mato Gros-so, 2001.
Salles AH, Reis GMCL, Zurlo MA. Hortomedicina do Cer-rado. Jardim Botânico de Brasília, p. 5, 1997.
Sattler SE, Gilliland LU, Magallanes-Lundback M, Pollard M, Della Penna D. Vitamin E is essential for seed longevity and for preventing lipid peroxidation during germination. The Plant Cell, v.16, n.6, p.1419-1432, 2004. https://doi.org/10.1105/tpc.021360
Stella JC, Battles JJ, Orr BK, McBride JR. Synchrony of seed dispersal, hydrology and local climate in a semi-arid river reach in California. Ecosystems, v.9, n.7, p.1200-1214, 2006. https://doi.org/10.1007/s10021-005-0138-y
SILVA CJ, SANCHES L, BLEICH ME, LOBO FA, NO-GUEIRA JS. Produção de serrapilheira no Cerrado e Floresta de Transição Amazônia-Cerrado do Centro-Oeste Brasileiro. Acta Amazonica, v.37, n.4, p.543-548, 2007. https://doi.org/10.1590/S0044-59672007000400009
Sólon S, Brandão LFG, De Siqueira JM. O gênero Cochlo-spermum Kunth com ênfase nos aspectos etnobotânicos, farmacológicos, toxicológicos e químicos de Cochlosper-mum regium (Mart. ex Schr.) Pilger. Revista Eletrônica de Farmácia, v.6, n.3, p.1-22, 2009. https://doi.org/10.5216/ref.v6i3.7649
Sólon S, Carollo CA, Brandão LFG, De Macedo CS, Klein A, Dias-Júnior CA, Siqueira JM. Phenolic derivatives and oth-er chemical compounds from Cochlospermum regium. Química Nova, v.35, n.6, p.1169-1172, 2012. http://dx.doi.org/10.1590/S0100-40422012000600019
Toledo MI, Siqueira JM, Araújo LCL, Oga S. Acute and subacute toxicitiy of Cochlospermum regium (Mart. e Schr.) Pilger. Phytotherapy Research, v.14, p.359-361, 2000. http://doi.org/10.1002/1099-1573(200008)14:5<359::AID-PTR642>3.0.CO;2-0
Tundisi JG, Tundisi TM. Limnologia. São Paulo: Oficina de Textos, 1ª Ed., 632p. 2008.
Vasconcelos Filho SC, Ferreira ALL, Vasconcelos JM, Silva LS, Pereira LCS. Secretory structures in Cochlospermum regium (Schrank) Pilg. (Bixaceae): Distribution and histo-chemistry. Journal of Medicinal Plant Research, v.8, n.26, p.947-952, 2014. https://10.5897/JMPR2014.5460
Viu AFM, Da Costa EA, Viu MAO, Campos LZdeO, Santos SC. Germinação e desenvolvimento de plântulas de [Cochlospermum regium (Schrank) Pilger] – (algodão-do-campo) em diferentes substratos. Revista Brasileira de Bio-ciências, v.5, supl.2, p.957-959, 2007.
Viecelli CA, Cruz-Silva CTA. Efeito da variação no potencial alelopático de Sálvia. Semina: Ciências Agrárias, v.30, n.1, p.39-46, 2009.
Yakubu MT, Bukoye BB. Abortifacient potentials of the aqueous extract of Bamusa vulgaris leaves in pregnant Dutch rabbits. Contraception, v.80, n.3, p.308-313, 2009. https://doi.org/10.1016/j.contraception.2009.03.003
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 - Journal of Biotechnology and Biodiversity
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY 4.0 at http://creativecommons.org/licenses/by/4.0/) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Authors are permitted and encouraged to post their work online (e.g. in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (Available at The Effect of Open Access, at http://opcit.eprints.org/oacitation-biblio.html).
