Lavandula dentata residue: flavonoids, in vitro antioxidant activity and in silico simulation
DOI:
https://doi.org/10.20873/jbb.uft.cemaf.v13n1.18662Keywords:
biological capacity, phenols, sustainabilityAbstract
This study presents an integrative approach to characterize and determine the antioxidant activity of extracts of second lavender extraction (Lavandula dentata). The objective of this study was to quantify the content of soluble solids as well as total flavonoids and antioxidant activity of ethanolic and isopropyl extracts of L. dentata residue. In this work, antioxidant activity assays, determination of total soluble solids and total flavonoids, molecular docking simulation and UV-Vis spectrum were performed of ethanolic and isopropyl extracts obtained from the residue from the steam distillation process of L. dentata. The analysis of the UV-Vis spectrum revealed an expected pattern, the highest content of soluble solids (59 mg/mL) and flavonoids (86.26 mg EQ/mL) was determined for the isopropyl extract formulated with 10% of the residue, this same extract had the highest antioxidant capacity (52%) in silico simulations revealed several hydrophobic interactions, especially alkyl, and pi-alkyl of 1,8-cineol and α-pinene. These results corroborate the statement that L. dentata is a promising source of compounds with antioxidant potential.
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