Pseudomonas aeruginosa: antigenic characterization and antibody production
DOI:
https://doi.org/10.20873/jbb.uft.cemaf.v8n1.ribeiroKeywords:
infections, multidrug resistant, vaccine, LPSAbstract
Pseudomonas aeruginosa has reduced over the years among infectious agents often isolated in hospital settings. Currently, nosocomial infections caused by P. aeruginosa pose a challenge for antimicrobial therapy. An alternative to the multiresistant microorganism was performed in search of vaccines. In this paper, check through the literature review or that there is concrete and the perspectives related to the characterization of P. aeruginosa antigens and by consequence of antibody production and applicability. Make a bibliographic survey in Portuguese and English periodicals from 1980 to 2019 and 19 works will be analyzed and inserted. In vaccination, available resources are based on antigens derived from virulence factor toxins known from P. aeruginosa species, such as; exotoxin-A, proteases and elastases, and components of LPS. There was a shortage in the literature regarding the subject. Research should be conducted on antigen characterization and by performing test production.
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